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There May Well Be Some Benefits of Medical Marijuana, Session Admits

Marijuana is one of the most widely used drugs the world over. This is especially true among the younger generation, despite it being illegal in most nations. In the U.S, some states have yet to legalize marijuana us, causing a bit of confusion among American citizens. Worse yet, U.S Attorney General Jeff Sessions had recently gone on record to support the use of medical marijuana, when he had previously been dead set against it. Let’s take a look at how he came about his decision.
Sessions’ View
On April 25th, 2018, Sessions went before the Senate Appropriations Commerce, Justice and Science Appropriations Subcommittee panel and acknowledged that indeed there are some benefits from medical marijuana. He went further to support the appropriateness of studying cannabis for medical uses. Many were a little taken aback as the Attorney General had previously gone on record to say that he did not believe that medical marijuana was a medicine.
During his speech, Sessions admitted having seen research indicating lower overdose deaths in states that allow marijuana use. However, he was fast to criticize the current use of cannabis, suggesting that it is not being used for medical purposes. This is not too shocking as indeed younger people seem to be using it more especially in states where marijuana use is legal. A recent poll on the matter asserts this claim as it found out that one in four young adults uses cannabis every so often.
Additionally, Sessions indicated that steps to license more marijuana growing entities would soon be taken. However, he had some conditions for this as they would be for marijuana research only. Also, he did not give a timeline on the same, raising some questions on his end game.
The Confusion
In 2016, the DEA enacted a policy that was intended to license more marijuana research growers. Since then, the agency has received at least 25 applications but has yet to act on any of them. According to the Washington Post, this delay has been caused by top Justice Department officials who stepped in to prevent DEA from approving them.
However, one can sympathize with Sessions’ dilemma as, during his answers to the Senate committee, he admitted that allowing the research would expose the U.S to the risk of violating international drug treaties. Furthermore, he seemed hesitant to give an actual timeline as he considered that most people who take medical marijuana do not have a prescription for it. In his view, it is just another excuse to get high within the confines of a medical prescription.
Advocates of marijuana being legalized were pleasantly surprised at his new stand. Considering that he had previously worked against their beliefs, this came as a good shocker. However, they urged the Justice Department to act on allowing cannabis research and broadening policy changes sooner. In their defense, they supported that marijuana does indeed help many patients, and the recent drag in research was a great hindrance to patients’ health.
Justin Strekal, NORML Political Director, told Marijuana Moment that what Americans needed was better research on consumer marijuana as well as lawful policies for legal markets. During his interview, he pointed out that the continued deliberations from the DoJ were affecting over two million registered medical marijuana patients in the legal markets.
In his testimony, AG Sessions told the subcommittee that the priority of drug agents and federal prosecutors was heroin, cocaine, fentanyl and methamphetamine, and not cannabis. However, he stated that if indeed cannabis agents ‘were illegally acting and violating federal law,’ their agents would work on that case.
Sessions remain opposed to the idea that cannabis is helping to address the U.S opioid addiction crisis. He still does not think that it is safe to use medical marijuana, which may indicate why his office is slow in giving a timeline for the research program to kick off. Despite studies showing that legalized medical cannabis has caused a reduction in opioid overdose, Sessions believes that this development will not be sustained in the long run. However, he acknowledged this and even asked his staff to look further into the matter, as he views science to be very important in combating drug addiction.
Many are confused as to how U.S Attorney General Sessions will tackle the research of medical marijuana. This is as a result of his change of heart in the matter, yet research is still on hold. However, patients of medical grade cannabis can rest assured that his changed views on the matter are the right step towards more research. It will take some time though.
 

A visit to dispensary in Colorado with Tony M. Fountain

Medical Marijuana, a Revolutionary Approach to Wellness

Cannabis and health? Necessity makes strange bedfellows indeed. But studies have been done over and over on this topic, and every time researchers find additional health benefits of marijuana. Today marijuana and its extracts are used to treat several health conditions and alleviate pain. Cannabis is saving lives. It has now been legalized in Georgia and other 25 states.
The lifeline from opiate addiction
Opiate addiction is now endemic, the number one cause of deaths in the United States. The primary medical interest in marijuana was its pain relieving abilities. Cannabis is a natural and efficient pain reliever. Patients suffering from chronic pain now no longer have to be prescribed the addictive drugs like Vicodin and Oxycodone. Then again, deaths due to narcotics overdose have reduced. There have not been any reported cases of death due to marijuana overdose. It is factually improbable to OD and dies from cannabis. Opioid addicts have realized that, and are now switching to medical marijuana. Recent studies show that opiates use and addiction has dropped in states that have legalized marijuana.

Tony Fountain of NOW entertainment thinks the legalization of medical marijuana is a move that that was long overdue. Growing up in my small town, I saw real close and personal what a nightmare opiate addiction is. I lost friends who were forced down that road.’ He says addiction was not the only problem; crime syndicates spread their tentacles riding on the wave of opiates. Tony is a pragmatic investor who believes that there is also a great economic potential to be tapped from medical marijuana.
Cancer treatment
Big news: recent studies reveal that cannabis extracts can cure cancer cells and prevent it from spreading. If this kind of research is anything to go by, we may have a way to suppress the grim reaper that is cancer. Presently, medical marijuana is widely used by cancer patients undergoing chemotherapy. It helps to reduce pain and improve their appetite. Beyond that, it reduces nausea and vomiting, giving cancer patients a better fighting chance. The FDA has approved two drugs made from marijuana extracts for use in chemotherapy. These are dronabinol and nabilone.

There have been many milestones in the research of medical marijuana. Today there is an increased use of cannabis in the treatment of mental disorders, HIV/AIDS, and Multiple Sclerosis. Today medical marijuana is openly prescribed to patients who have PTSD, Alzheimer’s disease, and other psychiatric disorders. It helps to reduce anxiety and other neurotic symptoms. Medical marijuana is also used in the treatment of HIV/AIDS. It helps to relieve pain and reduce nausea and vomiting. In multiple sclerosis, cannabis is used to reduce pain, muscle spasms and tremors.
CBD – the Holy Grail 
A chemical compound found in marijuana CBD, or cannabidiol makes it more than just a pain reliever. CBD is anti-inflammatory, antioxidant, anticonvulsant, antiemetic, and anxiolytic. Today manufacturers are extracting CBD from and packaging it in bottles as CBD oil, or as capsules. It is used to treat pain, mental illness, anxiety and skin conditions.
Legalities aside, marijuana can indeed be lifesaving.

How to Take Marijuana as Medicine

How to Take Marijuana as Medicine

Firstly, you’re going to need a medical marijuana card in most states. Secondly it can easily be argued that all marijuana use is medicinal or for health & wellness. Why? Simply because, even if you are using cannabis for the euphoric “high”, you are still getting the benefits of all the cannabinoids and terpenoids from the plant. The cannabidiol (CBD), cannabichromene (CBC), cannabigerol (CBG), caryophyllene, bisabolol etc. are all still doing their jobs and reducing inflammation, busting stress and helping put the endocannabinoid system (ECS) back into order.
As such, there is no one strict, definite way of taking marijuana as medicine – at least, not yet, anyway.. Now you have that here are some suggestions for taking marijuana as medicine …
Go for Whole Plant Extracts
If you’re looking at tinctures and the like, it is best to go for ones that have been made as a whole plant extract. This means all of the plant’s natural cannabinoids, terpenoids and flavonoids are kept, rather than being “stripped” for a particular cannabinoid (often CBD), and then having artificial flavors and synthesized terpenes added afterwards.
The reason for this is simple: isolated compounds are generally less effective, and having various cannabinoids and terpenoids helps the main cannabinoid you’re seeking do its job properly. There is some evidence showing that crude plant extracts have greater in vitro and/or in vivo activity than isolated compounds at equivalent doses. Jayden’s Juice and the tinctures made by CannaKids are great examples of high-quality whole plant extracts. Vaping flowers is also a good way of utilizing cannabinoids effectively.
You Don’t Have to Smoke …
Although there is no evidence linking cannabis smoke to cancer, it is understandable that many would want to avoid smoking, especially as cannabinoids and terpenoids can be lost vias combustion. Nowadays we have edibles, tinctures, topicals and a whole host of smoke-free ingestion methods.
However, it must be said: smoking cannabis can often be less overwhelming than edibles, and for some smoking it really is the best way of getting medicated. As everybody has a different constitution, some ways of taking marijuana are more effective than others. Edibles also take a long time to kick in, so the temptation to take more thinking, “This isn’t having any effect” is huge.
Go Slow …
Remember: you can always take more, but you can’t take less. Should this be your first time using medical marijuana, it is advisable to try out vaporizing first, as the dosage is easy to control. Just take one puff on a vape pen or whatever other type of vaporizer you’re using, wait 10-15 mins, then dose again. Build up slowly, and get a gauge of where your tolerance lies.
Should you want to go with edibles – and many people do due to discretion and their long-lasting effects – microdosing is ideal, and tinctures can provide similarly effective relief in a much more controllable manner. For those with aching muscles, there are medical marijuana-based topical creams out now as well!
Mood and Setting
Medical marijuana is best taken in a place where you’re most relaxed and comfortable. For many people, this is their own homes, which is a good thing, as this is the most discrete way of consuming cannabis as well.
Eating Properly
Granted, many of you will be using medical marijuana in order to get the munchies and be able to sit down for a proper meal, especially if you’ve been prescribed harsh drugs that can kill appetite or you’re going through chemotherapy. However, as with most things in life, using marijuana is possibly best done on a full stomach. Your energy levels are less likely to dissipate this way and the effects won’t be as overwhelming.
Take Note of Cannabinoid and Terpenoid Concentrations …
… As this is what will tell you the sort of effect a strain is likely to have, rather than the strain name or even its parentage (although the genetics do have an effect, but it’s a rough measure at best). Also, as everyone has a different ECS, different cannabinoid concentrations will treat different people differently!
For example, whilst most people seem to report a 1:1 CBD:THC ratio, others might find such a ratio to have no effect whatsoever. Those people will have to find their ideal ratio. Another thing to remember is that people often prefer different cannabinoid ratios for different times of day or for different environments. You might prefer a CBD-heavy indica for sleep and a THC-heavy sativa for socializing, whereas a 1:1 CBD:THC helps you keep functional and pain-free throughout the day.
Hopefully, this article has helped you clear up any questions on how to take marijuana as medicine. Should you wish to learn more, head on over to doctorfrank.com!

cancer marijuana

Cancer Treatments: Now With Marijuana

Marijuana is an old remedy.

Modern cancer patients aren’t the only people to understand the healing power of marijuana. Marijuana is the name given to the cannabis plant during 20th century prohibition. Cannabis grows wild in warm and tropical climates throughout the world and has been cultivated commercially for eons. Prohibition has given cannabis many other aliases as people developed code. Names like pot, grass, cannabis, weed, hemp, hash, hydro, ganja, and dozens of others all describe the same plant.
Records show marijuana has been used in herbal remedies dating back to the Chin Dynasty in China. Ancient doctors could see the effects of using cannabis as well as today and prescribed it for many maladies. The herb was so powerful that even the Romans put it in their medical texts.
Scientists have identified many biologically active components in marijuana that are the main reason it is so useful medically. These compounds are called cannabinoids. The two most studied of the hundred or so cannabinoids are delta-9-tetrahydrocannabinol (THC), and cannabidiol (CBD). Other cannabinoids are being studied but haven’t had the same amount of press or research put into them.

Is marijuana a legal treatment?

cancer treatmentAt this time, the US Drug Enforcement Administration (DEA) lists marijuana and cannabinoids as Schedule I controlled substances that cannot legally be prescribed, possessed, or sold under federal law. Whole or crude marijuana (including marijuana oil or hemp oil) are also not approved by the US Food and Drug Administration (FDA) for medical use whatsoever.
State laws have a little bit more play in them and diverge from the federal stance to different degrees. The use of marijuana to treat some medical conditions is legal in many states even though it remains federally banned. Each state has individual rules about how they deal with marijuana so it is important to research the specific rules for your state.
Dronabinol (pharmaceutical THC) and some synthetic cannabinoid drugs like Marinol are approved by the FDA. Marinol is used to relieve nausea and vomiting for chemotherapy patients in addition to being prescribed to AIDS patients for appetite stimulation.

Marijuana is more than THC.

Different compounds found in marijuana have affect the human body in different ways. For example, delta-9-tetrahydrocannabinol (THC) causes the mental high and can also relieve pain and nausea. At the same time it can reduce inflammation and act as an antioxidant. Cannabidiol (CBD) can help treat seizures, can reduce anxiety and paranoia, and can counteract the “high” caused by THC according to the American Cancer Society.
Different cultivars (strains or types) of marijuana can have varying amounts of the different cannabinoids. The specific ratio of cannabinoids produced by a plant is known as it’s strain profile and can be used to better judge what effects to expect from a specific strain.
The effects of marijuana also change depending on how it enters the body:

  • When inactivated or raw cannabis is eaten, the THC is absorbed poorly by the body. Once absorbed, it’s processed by the liver into a second psychoactive compound. The second substance acts on the brain to change mood and/or consciousness differently than THC.
  • When marijuana is smoked or vaporized, THC enters the bloodstream quickly, bypassing the liver at first. It is transported to the brain before the liver can convert a large amount of it into the second chemical. Because there is so much less of the second chemical, the high is stronger but fades quicker.

What can marijuana treat?

A number of studies using small groups of marijuana users found that cannabis can be helpful for treating nausea and vomiting from cancer chemotherapy. A few studies have found that smoked or vaped cannabis can be helpful in the treatment of neuropathic pain as well.
Smoked marijuana has also helped improve food intake in certain HIV patients during some studies. Clinical trials have also been shown marijuana extract users tended to need less pain medication than others. The pain relieving effects seem to be even better in the non-psychoactive cannabinoid CBD than with THC.

How does marijuana affect cancer?

According to the American Cancer Society, “…THC and other cannabinoids such as CBD slow growth and/or cause death in certain types of cancer cells growing in lab dishes. Some animal studies also suggest certain cannabinoids may slow growth and reduce spread of some forms of cancer.” While there have been some early clinical trials of cannabinoids in treating cancer, future studies are inevitable.
Most studies show cannabinoids can be safe in treating cancer. They do not however seem to help control or cure the disease. Relying on marijuana alone as treatment while avoiding or delaying conventional medical care for any issue (including cancer) may have serious health consequences.

What are the possible harms of marijuana?

While many insist marijuana can pose no harm to users, it is not true. The most common effect of marijuana is a feeling of euphoria. Yet the complex chemistry of the brain and cannabinoids indicates that there is a lot going on under the hood. Cannabis can lower the user’s control over movement, cause disorientation, and sometimes cause unpleasant thoughts or feelings of anxiety and paranoia. While the majority of users do not experience these negative effects, they are more common in new users who don’t understand their dosing requirements.
Smoked marijuana delivers THC and other cannabinoids to the body along with harmful substances. Tar is one of the substances found in both tobacco and cannabis smoke. Heavy users (more than one gram a day) of smoked cannabis also commonly report chronic bronchitis.

Make sure to do research.

Because marijuana plants come in different strains with different levels of active compounds, it can make each experience different. Even with good data from a state certified lab, the effects of a specific strain on a specific user can be very hard to predict. It can take time and experimentation to find the best treatment plan or strain for a specific issue.
Even though cannabis is not chemically addictive (like caffeine or an opioid) people can still become psychologically dependant. Users will not receive the life threatening withdraws like they do from cocaine but they may still feel the conditioned desire to use.  Treatments and attitudes toward addiction vary widely across countries and the globe. If you struggle with addiction or are interested in treating any malady, it is best to seek a spectrum of qualified professional help before committing to any treatment plan. Make sure to get more than your own opinion before you make potentially life altering decisions. Thanks for reading.

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Accidents and the Dangers of Driving on Weed

Most people have been taught that alcohol increases the risk of accidents.

Smoking and driving can get you a DUI for an accident even in states where cannabis is legal. Current state laws for marijuana have focused on regulating it like alcohol while on the road. This is especially true when it comes to consuming and driving. Yet evidence of marijuana’s culpability in on-road accidents is difficult to prove.
Many states have reduced penalties for cannabis related crimes over the last few years. Yet as states continue to loosen regulations on marijuana safety, law enforcement is struggling to figure out how to establish a legal limit for drivers. They have focused on setting a blood-content test just like the .08 limit for alcohol.
A new study shows the challenges in accurately testing drivers.
One of the most difficult parts of testing is developing a threshold for what’s considered too high to drive. The conductors of the study concluded that “THC concentrations drop rapidly during the time required to collect a blood specimen in the U.S., generally within two to four hours.”
The low amount of time cannabis remains active for oral tests using the drivers’ saliva make it harder to fail than traditional tests. Saliva tests can be done roadside without a long wait but researchers found oral tests don’t provide “a precise measure of the level of impairment.”
Politicians are hesitant to implement concentration-based cannabis-driving legislation because it might ” unfairly target individuals not acutely intoxicated, because residual THC can be detected in blood for up to a month of sustained abstinence in chronic frequent smokers.” Depending on the direction that the new Attorney General Jeff Sessions takes the Justice Department over the coming years, detecting residual cannabinoids may be more important than registering intoxication.

Smoking weed is not safe while driving.

Cannabis intoxication has been shown to mildly impair a drivers psychomotor skills. It doesn’t appear to be severe or long lasting though. In driving simulator tests, this impairment was typically manifested by decreasing driving speed and needing more time to respond to emergency situations.
Yet this impairment does not appear to play a significant role in on-road traffic accidents. A review of seven different studies involving 7,934 drivers showed in 2002, “Crash culpability studies have failed to demonstrate that drivers with cannabinoids in the blood are significantly more likely than drug-free drivers to be culpable in road crashes.” And it’s not like people haven’t tried to prove a link either.
A Massive body of research exists that explores the impact of marijuana on psychomotor skills and actual driving performance. Researchers have done driving simulator studies, on-road performance studies, crash culpability studies, and reviews of the existing evidence. To date, the result of this research has shown how mildly cannabis affects driving abilities but that won’t stop the cops from hauling you off for having it in your system if you get in an accident.

Bad accidents

Marijuana has a measurable yet relatively mild effect on psychomotor skills.

Yet it does not appear to play a significant role in vehicle crashes, particularly when compared to alcohol. Researchers conducting a study for the National Institute on Drug Abuse said alcohol “significantly increased lane departures/minimum and maximum lateral acceleration”. Cannabis did not have the same correlation between consumption and decreased performance.

Researchers for the Highway Traffic Safety Administration funded study concluded Cannabis-influenced drivers are better able to measure their intoxication “may attempt to drive more cautiously to compensate for impairing effects, whereas alcohol-influenced drivers often underestimate their impairment and take more risk.”

People keep studying the link between cannabis, alcohol and car accidents.

The prevalence of both alcohol and cannabis use and the extreme morbidity associated with car crashes has lead to repeated research on the link between the two. According to another study, “drunk drivers are involved in 25% of motor vehicle fatalities, and many accidents involve drivers who test positive for cannabis.”
The researchers say that while both alcohol and cannabis impair performance in a “dose-related fashion” the “effects of cannabis vary more between individuals than they do with alcohol because of tolerance, differences in smoking technique, and different absorptions of Δ9-tetrahydrocannabinol (THC), the active ingredient in marijuana.”
The effects of a cannabis “high” vary according to dose but are more pronounced with highly automatic driving functions than with more complex tasks.” Basically making it easier to focus on a plan than instinctively react to something. With alcohol the opposite pattern of impairment is produced and people get distracted easier.

Cannabis and alcohol have a synergistic effect.

Because of an increased awareness that they are impaired, “marijuana smokers tend to compensate more effectively while driving than drunks” by utilizing a variety of strategies. Mixing marijuana with alcohol removes the ability to use such strategies as the two substances increase the potency of the other when mixed.
Cannabis and alcohol work on many of the same levels in the brain and both inherently affect chemical production in the brain. Mixing cannabis and booze will amplify the effects of both and can lead to serious repercussions. While studies have been inconclusive regarding whether cannabis use causes an increased risk of accidents; in contrast, unanimity exists that alcohol use increases the risk of crashes.
In addition, the risk from driving under the influence of alcohol and cannabis together is higher than the risk of driving under the influence of either alone. One study even recommends that patients who smoke cannabis wait several hours before driving, and avoid combining the two drugs.

Even schools have studied how dangerous driving while high is.

The first study to analyze the effects of cannabis on driving was conducted by Researchers at the University of Iowa’s National Advanced Driving Simulator, sponsored by National Highway Traffic Safety Administration, National Institute of Drug Abuse, and the Office of National Drug Control Policy.
The researchers found that cannabis use caused almost no impairment. The impairment that it did cause was similar to the change observed while under the influence of a legal alcohol limit. They basically couldn’t get cannabis to impair driving as much as one beer.
They tested impairment mainly with a simulator. “Once in the simulator—a 1996 Malibu sedan mounted in a 24-feet diameter dome—the drivers were assessed on weaving within the lane, how often the car left the lane, and the speed of the weaving. Drivers with only alcohol in their systems showed impairment in all three areas while those strictly under the influence of vaporized cannabis only demonstrated problems weaving within the lane.”

More research is needed to find the right limits.

All these study’s findings show that alcohol is a much more dangerous drug than cannabis yet regulated in a more relaxed manner. While driving while under the influence of cannabis can still get you locked up, it is unclear how dangerous it is. More research is needed to show exactly how much cannabis should be legally allowable but for the time being, driving after consuming any cannabis remains illegal.
Until the whole world switches over to autonomous vehicles and we don’t have to worry about driver error any more, people are still going to get into accidents (sober or not). It is best not to contribute to the problem and simply don’t drive while high. You never know when you might need to instinctually react to something in your lane. Thanks for reading.

dea

DEA: Marijuana is Not a Gateway Drug

Marijuana has been called a gateway drug for over 80 years.

The battle lines were drawn long before anyone currently driving the gateway debate had assumed power. Political figures have demonized cannabis and those who consume it for almost a century and worked to create a massive industrial prison complex designed to harvest people. Low income and minority people have borne the brunt of the assault.
Americans have been tricked into accepting the most ridiculous claims about cannabis and a whole generation of people have grown up behind bars because of it. Politicians have used slippery speech to sway public opinion and outright changed the law in order to suite their desires for decades. When Reagan and Clinton enacted laws that put more people in jail than the Romans had slaves.
Larry Anslinger didn’t care about how many would suffer without the healing properties of cannabis, he was motivated by an zealous hatred for the plant to create the movie Reefer Madness. President Nixon was motivated by a religious desire to punish people regardless of what his own investigators proved. Reagan had no mercy for people caught in the crossfire when he enacted draconian mandatory punishments for minor drug infractions.gateway

We stand at the dawn of a new era of American drug policy.

Despite an abundance of empirical evidence about the medical benefit of cannabis from reputable medical professionals from the Shafer Commission to Sanjay Gupta, it remains a schedule 1 controlled substance. This classifies weed as having “no medical benefits” and creates massive hurdles for scientists and doctors looking to research cannabis. It also puts it in the same medical category as heroin.
With the rise of Trump and the appointment of Jeff Sessions to Attorney General, the entire industry is bracing for another impact. Part of the collective wince comes from the evasive actions of top officials on the matter through election season. Instead of giving clear messages about how they plan to pursue policy, government officials are as vague as possible about how they plan to pursue policy.
This evasive attitude has made many wary of the how the Trump Administration plans to deal with cannabis. Statements in the past by Jeff Sessions like “Good people don’t smoke marijuana.” and his past issues of discriminatory prosecution during the Civil Rights movement has helped to stir up old debates.

The debate surrounding legalizing marijuana has resurrected the Gateway Theory.

This theory presumes that experimenting with marijuana inevitably results in the use of harder drugs like cocaine, heroin and methamphetamine. Until recently, the DEA website contained dozens of lies and inaccuracies and it begrudgingly changed them only after being threatened with legal action.
Many people don’t know that it is illegal for federal agencies to spread incorrect information. Yet when it comes to cannabis, the Drug Enforcement Administration (DEA) has been doing it for years. In less than a month, a petition from Change.org calling on the DEA by a to stop lying about medical cannabis received 85,000+ signatures.
The petition was started by Americans for Safe Access (ASA), a nonprofit organization working to increase access to medical cannabis. “The DEA has actually admitted that the theories that cannabis use leads to harder drugs (gateway theory), long-term brain damage, psychosis, and other alleged harms, are not based in scientific fact, and yet they keep distributing this false information”, says ASA. “[W]e have found 25 instances of these false claims on their website.”

The petition for updated information was direct and their arguments were air-tight.

The group argued that the document previously known as “The Dangers and Consequences of Marijuana Abuse,” had a few inaccurate claims about cannabis.  They showed how the page was in violation of the Information Quality Act which requires that administrative agencies provide accurate information to the public. The DEA also had to respond to requests for correction of information within 60 days.
A separate petition was filed by the Department of Justice demanding that the DEA immediately update misinformation about cannabis. While neither the DEA nor the DOJ responded to ASA’s request, the document which contained the majority of the inaccurate statements was removed from their website.
But the governement is made up of more people than ever before. There is a lot of room for competing ideologies and goals to play out. A key observation of the Shafer Commission is that many of the risks of drug use are the result of drug policy/enforcement rather than from the drugs themselves.

The “gateway drug” stigma refuses to die.

A prime example of how this stigma presents itself is New York governor Andrew Cuomo. He wants to keep cannabis illegal in New York State because it “leads to other drugs and there’s a lot of truth to proof that that’s true.” He holds this view despite the results of a major study on medical marijuana conducted by the venerable Institute of Medicine, which included an examination of marijuana’s potential to lead to abusing other drugs.
The study found that “There is no conclusive evidence that the drug effects of marijuana are causally linked to the subsequent abuse of other illicit drugs.” Even the DEA has gone on record to say “Little evidence supports the hypothesis that initiation of marijuana use leads to an abuse disorder with other illicit substances,” while refusing to reschedule cannabis in August of 2016.
The continuing stigma prevents meaningful reform of marijuana laws by perpetuating harmful misinformation.  A Rasmussen poll found that a large percentage of Americans believe the gateway argument. Nearly half of voters (46%) believed marijuana use leads to harder drugs. Thirty-seven percent (37%) did not see marijuana as a “gateway” drug.

Patterns in progression of drug use are strikingly regular.

Because it is the most widely used illicit drug, marijuana is predictably the first illicit drug most people come across. Not surprisingly, most users of other illicit drugs used marijuana before the harder stuff. In fact, most adult users begin with alcohol and nicotine long before moving on to cannabis and other illicit drugs.
In 2006, the University of Pittsburgh released a thorough study which researchers spent 12 years putting together. They tracked a group of subjects from adolescence into adulthood and documented the initiation and progression of their drug use. The researchers reported that the gateway theory was not only wrong, but also detrimental to properly understanding and addressing drug abuse.
The myth of the Gateway effect needs to be put to rest once and for all. The more research that is conducted the clearer it becomes that cannabis use does not lead to abuse of other drugs. Some promising research has also shown that cannabis can actually help people kick the other stuff like heroine. As more and more states legalize medical and recreational marijuana, it is more important than ever to put the gateway myth to rest. Thanks for reading.
 

canna

Terpenes: The Arousing Aroma of Cannabis

Have you ever wondered what makes cannabis smell the way it does?

There is a lot of chemistry when it comes to terpenes. There is still a lot to unlock about how our bodies process the chemicals that make things smell. We call these chemicals aromatics and terpenes are the specific types of aromatics produced by plants including cannabis.
Many recent advancements in the science of biology and biochemistry have opened windows into how we experience terpenes. Most people can tell the difference between the smell of lemons and mushrooms because the chemicals they produce interact with our bodies differently. They interact with our endocannabinoid system through CB-1 and CB-2 receptors the same way THC and CBD do.

How do terpenes work?

Terpenes have a synergistic effect with cannabinoids as their complex chemistry is able to shift and flex. Because of their flexibility, they can be used by the body to work for many different uses. Terpenes can affect dopamine and serotonin production and destruction while limonene can increase serotonin production. This is why different strains not only smell and taste different, but also have different affects on mood or sensation.
While over 200 terpenes occur in different concentrations in any given strain, there are a few primary terpenes that produce the greatest concentrations, and about 20 more secondary terpenes that occur in lesser concentrations. Each terpene has a specific purpose and more research is needed to reveal the true complexity of their chemistry.

What are the primary terpenes?

Of all the hundreds of terpenes, there are only a few that are produced in any great abundance. There are about 12 main terpenes in cannabis. Different strains produce terpenes in different amounts and are therefore specialized to treat different maladies. Here are the most common terpenes and what they do.
Myrcene: Is an effective anti inflammatory. It also works as a sedative and muscle relaxer.
Linalool: Can be used as an anti inflammatory and can also modulate motor movements.
Limonene: Can be used to help promote weight loss, prevent and treat cancer, and treat bronchitis.
Alpha Bisabolol: Can heal wounds, fights bacteria, and can also be used a deodorizer.
Delta 3 Carene: Is an effective anti inflammatory. It is also known to dry fluids like tears, running noses, and menstrual flows.
Borneol: Can be used as an analgesic, anti-septic, and bronchodilator.
Pinene: Has anti-inflammatory properties.
Eucalyptol: Is used in cough suppressants, mouthwash, and body powder.
Terpineol: Contains antioxidant properties.
Caryophyllene: May help treat anxiety and depression.
Camphene: Is known to possess anti-inflammatory and antibiotic characteristics.

Testing for terpenes can be done two ways.

Most consumers have a passing knowledge of what terpenes they want. They try a few strains and develop a preference for one over another. A quick sniff of a sample is all that is needed for a broad sense of what is present. Trying to peel apart the individual layers takes a more nuanced approach though.
Myrcene and linalool are some of cannabis’s most abundant terpenes. Myrcene smells musky, like cloves or an earthy, herbal scent. Some even say it has notes of citrus and tropical fruit. Linalool on the other hand smells like a  candy or  a sweet floral element. The more fragrant a strain, the more terpenes are present and active.
Because of how many different aromatic terpenes cannabis produces, it can be difficult to determine the exact mix of terpenes by smell alone. Most producers or distributors rely on chemical analysis. They get the exact level of terpenes through a report from a certified testing lab. The same labs that test for THC and CBD content are often equipped to also perform terpene analysis for a small fee.

Plants produce terpenes for a variety of reasons.

Plants can’t run away from predators or bad weather. Because they can’t flee, they have developed many ways to deal with the inevitable. One of the ways plants cope is by producing chemicals like cannabinoids and terpenes. Terpenes like pinene and limonene are able to ward off plant predators while linalool and myrcene can help the plant heal from injury.
Plants can also use terpenes to call for help. There is evidence that even corn uses terpenes like those found in cannabis to protect itself from predators. It doesn’t use the terpene to kill anything, it uses it to call for reinforcements. Corn roots damaged by pesky caterpillars emit caryophyllene. This terpene attract predatory wasps that then attack the caterpillars.

Different plants produce the same terpenes.

Cannabis produces terpenes in the same trichomes that it uses to produce cannabinoids like THC and CBD. The cannabis plant smells strongest during flowering because that is when the most trichomes are active. Natural variation and forced breeding techniques have allowed people to design plants based on cannabinoid content as well as terpene content.
Biology is complex but there are repeating patterns. Most plants require the same chemicals (Nitrogen, Phosphorus and Potassium) as they do to produce smells (terpenes). Cannabis produces the same terpenes as other plants, just in different amounts.

Terpenes enhance the effects of cannabinoids.

Take myrcene, it occurs in fragrant plants and herbs like mangoes, hops, bay laurel leaves, thyme, lemongrass, and basil. It is naturally synergistic with THC and allows cannabinoids to more easily bridge the blood-brain barrier. Myrcene is present in most cannabis although it is a dominant terpene in Pure Kush, Jack Herer and many other strains.
Over generations of breeding, cannabis cultivators have selectively bred plants to produce high levels of specific mixes of terpenes. Strains like Lemon Skunk and Sour Lemon have higher levels of limonene in them while Dog Walker and Skunk normally produce more myrcene.

Orin-Ray Terpenes

Do terpenes just make things smelly?

Terpenes determine many of the effects attributed to specific strains. While two samples may have the same THC content, if their terpenes profile (mix of terpenes present) are different, the samples will affect someone in different ways. Strains like Granddaddy Purps or OG Kush are generally sedating while Sour Diesel and Strawberry Cough tend to increase alertness.
Humans have inhaled terpenes, including linalool, since ancient times to help relieve stress, fight inflammation, and combat depression. Linalool specifically has been the subject of many studies. Some, like this one where scientists had lab rats inhale linalool while exposing them to stressful conditions, reported that linalool returned their immune system stress levels to near-normal.
We still need to do more research to find all of the ways that terpenes interact with our bodies. As legalization sweeps the country, hope for more research funding is growing. For now, people in states that have legalized cannabis in some way can begin doing anecdotal research themselves. Thanks for reading.

cann history

A History of Medical Cannabis Part 2: Modern Cannabis

In Part 1 we talked about ancient cannabis and how it has been used throughout the ages.

Today we are going to talk about modern cannabis and how it moved from prominence as a medicine to a recreational drug. Yet medical cannabis is not relegated to the ancient past. Modern medicine uses the term marijuana instead of the ancient name: cannabis but it means the same thing.
The original name can be traced back to the Greek physician Pedanius Dioscorides. He was a roman army doctor from around 40-90AD who traveled widely on campaigns throughout the Roman empire. He wrote the medical text that virtually all others were based on for over a thousand years and had a special entry for both male and female cannabis plants. It wasn’t until the 1930’s when the plant became known a marijuana in an effort to re-brand it. But I’m getting ahead of myself.

By 1621, medical marijuana had made its way into the English Mental Health Book.

Cannabis was entered into one of the most popular medicinal textbooks from the era to treat depression. Because of the work of an Irish doctor working for a shipping company during the colonization of the new world, medical cannabis moved to the Americas.
Cannabis treatments were a staple of a professional doctors curriculum up through the industrial revolution.  Before Alaska and Hawaii were states, America had laws on the books that supported medical marijuana in all 48 states. Cannabis was not seen as a recreational drug, it was medicine with little risk of side effects.

But in 1936 all that changed.

Pressure was being placed on the U.S. by the international community to sign the International Treaty on Controlled Substances. While not directly listing cannabis as a controlled substance, the treaty forced all countries that signed to adopt similar drug policies. Propagandists later used the treaty to get cannabis banned across the developed world.
A very popular anti-marijuana campaign burned through the nation. Funded by the government and directed by the talented propagandist Larry Anslinger, “Reefer Madness” was a sensational tale about marijuana. It featured the plant ruining people’s lives through sex, insanity, and horrific acts of violence. Although Reefer Madness was a work of pure fiction,  it was accepted by a whole generation as fact with the tenacity of religious convictions. The influential power of the Reefer Madness propaganda laid the groundwork for Larry Anslinger to get cannabis banned.
Larry Anslinger was a potent propagandist that was able to convince the developed world to outright ban cannabis use, cultivation and distribution. He used a mixed media of propaganda to accomplish this. Anslinger was a master of using media and used the newspapers, radio and television to spread a web of half-truths and outright lies.
After spreading a racially motivated panic with the Reefer Madness propaganda, Anslinger convince the U.S. to pass the Marijuana Tax Act of 1937. Anslinger provided his political masters a new way to target their political opponents voting base. The politically motivated police force acted quickly on the new laws to target the poor.

The Marijuana Tax Stamp Act brought America Modern Cannabis.

On the day the Marijuana Tax Stamp Act was enacted (Oct. 2, 1937) the FBI and Denver Colorado police raided the Lexington Hotel. They arrested a man named Samuel R. Caldwell for selling modern cannabis. He was a 58 year-old unemployed laborer. Three days later, on Oct. 5, 1937 Caldwell became the first person convicted under U.S. federal law of distributing cannabis.
In 1942, cannabis was removed from the U.S. Pharmacopeia. When that happened, cannabis lost the last vestiges of medical legitimacy. Because of the International Treaty on Controlled Substances, most of the other countries in the developed world were forced to enact similar rules.

Over the next decades, criminalization of cannabis continued.

As more and more regulations were heaped on medical practitioners, they became unable to prescribe cannabis. Legal penalties increased massively with the Boggs Act of 1951. It established minimum prison sentences for simple possession of cannabis. Thanks in great part to Anslinger’s work, cannabis was classified as a schedule 1 controlled substance in 1970.
Schedule 1 substances are substances no medical benefit and high risk of abuse. The controlled Substances Act of 1970 Classified Marijuana as a having “No Accepted Medical Use”. After the passing of the Substances Act, medical practitioners were barred from prescribing modern cannabis for any medication, effectively removing the oldest known medicine from a whole generation of healers across the globe.
In 1971, the Shafer Commission was created by the U.S. president to determine the merit of criminalizing cannabis. The Shafer Commission was bi-partisan and overseen by congress. President Nixon himself ordered it to determine “if the personal use of marijuana should be criminalized.” The commission came back with an answer and Nixon ignored it because he didn’t like that they believed there was no reason to scale up action against users.
In 1971 president Nixon chose to aggressively pursue action against cannabis consumers by declaring the War on Drugs. Motivated by personal prejudice political corruption, he saw marijuana as a way to get at his political opponents. He even admitted at the time that his reasons for attacking cannabis users and increasing penalties was motivated by personal directives.

Nixon acknowledged his action was not based on empirical evidence.

He increased criminalization despite the commission he put together telling him officially and unequivocally that cannabis use should not be criminalized. Over the next two years, the Nixon built a force specifically designed to scale up violence against modern cannabis users.
The Department of Drug Enforcement (DEA) was established in 1973 by merging the Bureau of Narcotics and Dangerous Drugs (BNND) and the Office of Drug Abuse Law Enforcement (ODALE) into a single agency. It comes as no surprise that the DEA continues to aggressively pursue cannabis consumers, producers and distributors to this day. They use every tool at their disposal regardless of legality or constitutionality to continue the criminalization of marijuana.
Things continued to go downhill for cannabis in the coming years. It wasn’t until 1976 that Robert Randall (who was afflicted by glaucoma) used the Common Law Doctrine of Necessity (US v. Randall) to defend himself against criminal charges of marijuana cultivation. In 1976, federal Judge James Washington made waves with his ruling. Judge Washington ruled that Randall’s use of modern cannabis constituted a ‘medical necessity’ and the case was thrown out.
Modern cannabis 2

The next milestone for modern cannabis crusaders came in the winter of 1991.

Modern cannabis took a step forward with the passing of medical marijuana reform in California. The first medical marijuana initiative was called Proposition P and was in San Francisco. It passed with an overwhelming 79% of the vote in November of 1991.
Proposition P called on the State of California and the California Medical Association to restore hemp medical to the list of available medicines in California, and to stop penalizing physicians for prescribing hemp for medical purposes. It only effected San Francisco but the cogs of bureaucracy had been activated. It would take another 5 years for legislation to go statewide.
Voters in California passed the first statewide medical marijuana initiative on November 5, 1996. Known as Proposition 215, it permitted patients and their primary caregivers to possess and cultivate marijuana for the treatment of AIDS, cancer, muscle spasms, migraines, and several other disorders. It also protected doctors from state sponsored punishment if they recommended marijuana to their patients.

The wheels of bureaucracy turn slowly.

In September of 1998, the House of Representatives debated a resolution called H.J.Res. 117. They passed H.J.Res 117 at the same time Oregon, Washington and Alaska provided their medical marijuana programs. In H.J.Res. 117, Congress declared support for the existing federal drug approval process.
They decide not to reschedule marijuana despite the overwhelming evidence coming forth that it should be decriminalized. While cannabis is classified as having no medical benefit, the United States Department of Health and Human Services) currently holds a patent on medical cannabis.
Patent No. 6630507 covers the use of cannabinoids for treating a wide range of diseases and was submitted to the patent office in 1999. The Department of Health and Human Services was awarded the patent in 2003. Yet the Department of Health is not the only regulatory agency that has chosen to abandon science, compassion and reason.
Modern Cannabis

In 2002, the FDA decided how to use modern cannabis in a study.

They decided that shipping 300 pre-rolled joints to patients in metal canisters was the best way to judge modern cannabis. The material was frequently two or more years old upon receipt by patients and a close inspection of the contents of NIDA-supplied cannabis cigarettes revealed them to be a crude mixture of leaf with abundant stem and seeds.
The study concluded that “cannabis smoking, even of a crude, low-grade product, provides effective symptomatic relief of pain, muscle spasms, and intraocular pressure elevations…” and that “clinical cannabis patients are able to reduce or eliminate other prescription medicines and their accompanying side effects.” The FDA report was ignored by those in power and cannabis remained a schedule 1 controlled substance despite the undeniable evidence.
The DEA has still not reclassified cannabis. It remains a holistic herb used throughout time as a medicine that current U.S. legislators are violently opposed to. While international progress has been made with the UK rescheduling cannabis to Class B and the Netherlands also making great strides in medicinal research, the U.S. still struggles to come into the light. Use of scientific reasoning is about to get even harder for the U.S. government as President Trump decides who will take the reigns of power. Yet his choice of Jim O’Neill to head the FDA (who openly supports cannabis legalization) gives modern cannabis hope for the future. Only time will tell. Thanks for reading.
Featured image: shutterstock

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CBD: How Cannabidiol (CBD) is Natures Best Healing Compound

What is CBD?

Cannabidiol (CBD) is a naturally occurring compound found in cannabis plants.Scientific research over the last few decades has shown that Cannabidiol has dozens of medical benefits. Cannabidiol is one of over 60 compounds found in cannabis.  Both THC and CBD belong to a class of molecules called cannabinoids.
Of the known cannabinoid compounds, CBD and THC are usually present in the highest concentrations, and are therefore the most recognized and studied. The difference between CBD and THC comes down to how they interact with the cannabinoid 1 (CB1) receptors. Cannabidiol inhibits the interaction of CB-1 receptors throughout the body with a major focus on receptors in the central nervous system.
CBD Flower

How does CBD work in the body?

Cannabinoid receptors are cell membrane receptors  that contain transmembrane spanning properties. Cannabinoid receptors are activated by three groups of ligands (a molecule that binds to another molecule):  endocannabinoids that are produced inside the mammalian body, cannabinoids produced in plants and synthetic cannabinoids. Because CB-1 receptors bind with all three types of cannabinoids, one source can be supplemented for the other to provide medical benefit to patients.
The endocannabinoid system is a vast network of cell receptor proteins and serves many functions. CB-1 receptors are heavily concentrated in the central nervous system. Others types of cannabinoid receptors are found all over the body. They’re in every humans skin, digestive tract, and even in their reproductive organs. All of the endocannabinoids and plant cannabinoids bind to fatty compounds in the body. The binding properties of cannabinoids are why THC and CBD remain in a person’s system for so long.

How does CBD work in the brain?

Cannabidiol has low binding affinity for CB1 receptors. THC binds well with CB1 cannabinoid receptors but CBD does not. This is why one (THC) will cause a high and the other (CBD) will not. While this makes Cannabidiol a bad choice for recreational users, it is a significant advantage for use as a medicine. The high associated with cannabis is generally considered a side effect.
Since health professionals prefer treatments with minimal side effects. CBD is seen by most medical professionals as preferable to THC. CBD is non-psychoactive because it doesn’t act on the same pathways as THC. These pathways, called CB1 receptors, are highly concentrated in the brain and are responsible for the mind-altering effects of THC.
CBD Flower 1

What does CBD do?

The fact that Cannabidiol-rich cannabis is non-psychoactive or less psychoactive than THC-dominant strains makes it an appealing option for patients who want to avoid the stereotypical feelings associated with consuming cannabis.
Scientific and clinical research underscores Cannabidiol’s potential as a treatment for a wide range of conditions. People looking for relief from inflammation, pain, anxiety, psychosis, seizures, and other conditions without disconcerting feelings of lethargy find Cannabidiol to be an effective treatment.
Conditions including arthritis, diabetes, alcoholism, MS, chronic pain, schizophrenia, PTSD, depression, antibiotic-resistant infections, epilepsy, and other neurological disorders find the most relief from treatments. This is because CBD has demonstrable neuroprotective and neurogenic effects along with anti-cancer properties. These properties are currently being investigated at several academic research centers around the world.

How does CBD treat all these health issues?

The biggest distinction between CBD vs. THC comes down to a basic difference in how each one interacts with cannabinoid 1 (CB1) receptors. THC binds well with CB1 cannabinoid receptors while CBD does not. Think of it like an electrical plug connecting to an outlet.
A THC molecule is perfectly sized to connect with CB1 receptors. When that connection happens, THC stimulates those CB1 receptors like turning on a switch. THC works to activate those CB1 receptors.Cannabidiol works in a different way. It doesn’t act directly to activate or suppress CB1 receptors. Instead, it acts to suppress the CB1-activating qualities of a cannabinoid like THC.  So while THC turns on CB-1 receptors like sticking a key in an outlet, CBD blocks the outlet.

If CBD is so good, why isn’t it more mainstream?

Even though CBD shows great promise as a medicine, it remains illegal in most of the world. CBD is classified as a Schedule I drug (right beside THC) in the United States and a Schedule II drug in Canada and the UK.
The US government has been studying CBD for a while and fund most of the science going on stateside due to the difficulties associated in researching a schedule 1 substance. Even with the challenges, intrepid researchers have identified dozens of conditions that can be treated or cured using Cannabidiol.
A team of researchers at the California Pacific Medical Center, led by Dr. Sean McAllister, has stated that they hope to begin trials on CBD as a breast cancer therapy. Due to the challenges of navigating the FDA, they are fighting an uphill battle.

If CBD is great as medicine, why aren’t more drug companies using it?

All is not dark for CBD research. The U.S. Food and Drug Administration recently approved a request for a clinical trial of a CBD based drug. The drug in question is a pharmaceutical version of CBD used to treat children afflicted with rare forms of epilepsy. The drug is called Epidiolex and is made by GW Pharmaceuticals. GW Pharmaceuticals also makes another cannabis-based drug called Sativex.
Even with approval of trials for Cannabidiol based meds, the U.S. Drug Enforcement Agency (DEA) made it clear that marijuana-based extract is still considered a Schedule I drug under federal law. They made sure to say in a Dec. 2016 address that the ban includes CBD oils and other types of CBD-rich extracts.

What does the future of CBD look like?

In general, far more research is needed to figure out all of the effects cannabis has on our bodies. But, to say that our overall understanding of CBD is “lacking” would be an understatement. In the midst of medical and recreational legalization happening in the US state by state, the federal stance on cannabis remains staunchly opposed. While the UK classifies CBD as a schedule 2 substance, the US still tightly holds to its schedule 1 status of all things cannabis.
A pharmaceutical version of Cannabidiolwas recently developed by a drug company based in the UK. The UK based company, GW Pharmaceuticals, is now funding clinical trials on Cannabidiol as a treatment for schizophrenia and certain types of epilepsy through the significantly easier UK process.
Only time will tell if cannabis will become a mainstream medical tool in the future. With political pressure and overwhelming public support for legalization, there has been a lot of gains in recent years. As legislation moves cannabis out of the darkness and into the limelight, government agencies like the FDA will have to reevaluate how they have classified cannabis. Thanks for reading.